My final blog in this series on biologic strategies for repairing joint damage focuses on leading edge treatments designed to stimulate the regeneration of new hyaline cartilage: Osteochondral Autograft Transplantation (OATS or Mosaicplasty), Osteochondral Allograft Transplantation, Autologous Chondrocyte Implantation (ACI) and Stem Cell and Tissue engineering.